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β-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients

There is an increasing need to identify new biomarkers in colorectal cancer (CRC) to further characterize this malignancy. β-catenin plays a central role in the Wnt signaling pathway. It also binds Na(+)/H(+) exchanger regulating factor 1 (NHERF1) and interacts with the RAS-association domain family...

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Detalles Bibliográficos
Autores principales: Schirosi, Laura, Mazzotta, Annalisa, Opinto, Giuseppina, Pinto, Rosamaria, Graziano, Giusi, Tommasi, Stefania, Fucci, Livia, Simone, Giovanni, Mangia, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356523/
https://www.ncbi.nlm.nih.gov/pubmed/27765918
http://dx.doi.org/10.18632/oncotarget.12280