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B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines

In spite of remarkable preclinical efficacy, DNA vaccination has demonstrated low immunogenicity in humans. While efforts have focused on increasing cross-presentation of DNA-encoded antigens, efforts to increase DNA vaccine immunogenicity by targeting direct presentation have remained mostly unexpl...

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Detalles Bibliográficos
Autores principales: Colluru, Viswa Teja, McNeel, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356528/
https://www.ncbi.nlm.nih.gov/pubmed/27661128
http://dx.doi.org/10.18632/oncotarget.12178