Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis

Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays an essential role in enabling eukaryotic organisms to adapt to nutrient deprivation and other forms of environmental stress. In metazoan organisms, autophagy is essential for differentiation and normal development; how...

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Detalles Bibliográficos
Autores principales: Lee, Eunmyong, Wei, Yongjie, Zou, Zhongju, Tucker, Kathryn, Rakheja, Dinesh, Levine, Beth, Amatruda, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Autophagy and Cell Death
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356529/
https://www.ncbi.nlm.nih.gov/pubmed/27655644
http://dx.doi.org/10.18632/oncotarget.12084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356529/
https://www.ncbi.nlm.nih.gov/pubmed/27655644
http://dx.doi.org/10.18632/oncotarget.12084

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