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Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis
Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays an essential role in enabling eukaryotic organisms to adapt to nutrient deprivation and other forms of environmental stress. In metazoan organisms, autophagy is essential for differentiation and normal development; how...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356529/ https://www.ncbi.nlm.nih.gov/pubmed/27655644 http://dx.doi.org/10.18632/oncotarget.12084 |