Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion

Replication fork-associated factors promote genome integrity and protect against cancer. Mutations in the DDX11 helicase and the ESCO2 acetyltransferase also cause related developmental disorders classified as cohesinopathies. Here we generated vertebrate model cell lines of these disorders and cohe...

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Detalles Bibliográficos
Autores principales: Abe, Takuya, Kawasumi, Ryotaro, Arakawa, Hiroshi, Hori, Tetsuya, Shirahige, Katsuhiko, Losada, Ana, Fukagawa, Tatsuo, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356530/
https://www.ncbi.nlm.nih.gov/pubmed/27636994
http://dx.doi.org/10.18632/oncotarget.11982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356530/
https://www.ncbi.nlm.nih.gov/pubmed/27636994
http://dx.doi.org/10.18632/oncotarget.11982

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