Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation

Developing the Wnt pathway inhibitors has been considered as a therapeutic approach for cancers and other Wnt-related diseases. Previously we found that the G-rich sequence of WNT1 promoter is capable of forming G-quadruplex structure and stabilizing agents for Wnt1-mediated signaling pathway. Using...

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Detalles Bibliográficos
Autores principales: Chang, Lien-Cheng, Chen, Tsung-Chih, Chen, Shiag-Jiun, Chen, Chun-Liang, Lee, Chia-Chung, Wu, Shih-Hsiung, Yen, Yun, Huang, Hsu-Shan, Lin, Jing-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356533/
https://www.ncbi.nlm.nih.gov/pubmed/27626678
http://dx.doi.org/10.18632/oncotarget.6622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356533/
https://www.ncbi.nlm.nih.gov/pubmed/27626678
http://dx.doi.org/10.18632/oncotarget.6622

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