The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription

The unrestrained proliferation of cancer cells requires a high level of ribosome biogenesis. The first stage of ribosome biogenesis is the transcription of the large ribosomal RNAs (rRNAs); the structural and functional components of the ribosome. Transcription of rRNA is carried out by RNA polymera...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnston, Rebecca, D'Costa, Zenobia, Ray, Swagat, Gorski, Julia, Harkin, D. Paul, Mullan, Paul, Panov, Konstantin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356541/
https://www.ncbi.nlm.nih.gov/pubmed/27589844
http://dx.doi.org/10.18632/oncotarget.11770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356541/
https://www.ncbi.nlm.nih.gov/pubmed/27589844
http://dx.doi.org/10.18632/oncotarget.11770

Ejemplares similares