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The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription

The unrestrained proliferation of cancer cells requires a high level of ribosome biogenesis. The first stage of ribosome biogenesis is the transcription of the large ribosomal RNAs (rRNAs); the structural and functional components of the ribosome. Transcription of rRNA is carried out by RNA polymera...

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Detalles Bibliográficos
Autores principales:	Johnston, Rebecca, D'Costa, Zenobia, Ray, Swagat, Gorski, Julia, Harkin, D. Paul, Mullan, Paul, Panov, Konstantin I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356541/ https://www.ncbi.nlm.nih.gov/pubmed/27589844 http://dx.doi.org/10.18632/oncotarget.11770

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