New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells

Drug resistance is an important open problem in cancer treatment. In recent years, the heat shock protein HSP27 (HSPB1) was identified as a key player driving resistance development. HSP27 is overexpressed in many cancer types and influences cellular processes such as apoptosis, DNA repair, recombin...

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Detalles Bibliográficos
Autores principales: Heinrich, Jörg C., Donakonda, Sainitin, Haupt, V. Joachim, Lennig, Petra, Zhang, Yixin, Schroeder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356546/
https://www.ncbi.nlm.nih.gov/pubmed/27626687
http://dx.doi.org/10.18632/oncotarget.11905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356546/
https://www.ncbi.nlm.nih.gov/pubmed/27626687
http://dx.doi.org/10.18632/oncotarget.11905

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