Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels

Radiotherapy is generally applied in the treatment of esophageal squamous cell carcinoma (ESCC). However, the radioresistance of ESCC still remains an obstacle for the curative effect of this treatment. We hypothesized that diisopropylamine dichloroacetate (DADA), an inhibitor of pyruvate dehydrogen...

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Detalles Bibliográficos
Autores principales: Dong, Gaochao, Chen, Qiang, Jiang, Feng, Yu, Decai, Mao, Qixing, Xia, Wenjie, Shi, Run, Wang, Jie, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356547/
https://www.ncbi.nlm.nih.gov/pubmed/27626688
http://dx.doi.org/10.18632/oncotarget.11906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356547/
https://www.ncbi.nlm.nih.gov/pubmed/27626688
http://dx.doi.org/10.18632/oncotarget.11906

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