Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo

Hepatitis B virus (HBV) barely induces host interferon (IFN)-stimulated genes (ISGs), which allows efficient HBV replication in the immortalized mouse hepatocytes as per human hepatocytes. Here we found that transfection of Isg20 plasmid robustly inhibits the HBV replication in HBV-infected hepatocy...

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Detalles Bibliográficos
Autores principales: Leong, Chean Ring, Funami, Kenji, Oshiumi, Hiroyuki, Mengao, Deng, Takaki, Hiromi, Matsumoto, Misako, Aly, Hussein H., Watashi, Koichi, Chayama, Kazuaki, Seya, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356548/
https://www.ncbi.nlm.nih.gov/pubmed/27626689
http://dx.doi.org/10.18632/oncotarget.11907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356548/
https://www.ncbi.nlm.nih.gov/pubmed/27626689
http://dx.doi.org/10.18632/oncotarget.11907

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