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Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo
Hepatitis B virus (HBV) barely induces host interferon (IFN)-stimulated genes (ISGs), which allows efficient HBV replication in the immortalized mouse hepatocytes as per human hepatocytes. Here we found that transfection of Isg20 plasmid robustly inhibits the HBV replication in HBV-infected hepatocy...
Autores principales: | Leong, Chean Ring, Funami, Kenji, Oshiumi, Hiroyuki, Mengao, Deng, Takaki, Hiromi, Matsumoto, Misako, Aly, Hussein H., Watashi, Koichi, Chayama, Kazuaki, Seya, Tsukasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356548/ https://www.ncbi.nlm.nih.gov/pubmed/27626689 http://dx.doi.org/10.18632/oncotarget.11907 |
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