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Galectin-3 supports stemness in ovarian cancer stem cells by activation of the Notch1 intracellular domain

Ovarian cancer is the most lethal gynecologic disease because usually, it is lately sensed, easily acquires chemoresistance, and has a high recurrence rate. Recent studies suggest that ovarian cancer stem cells (CSCs) are involved in these malignancies. Here, we demonstrated that galectin-3 maintain...

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Detalles Bibliográficos
Autores principales: Kang, Hyeok Gu, Kim, Da-Hyun, Kim, Seok-Jun, Cho, Yunhee, Jung, Junghyun, Jang, Wonhee, Chun, Kyung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356551/
https://www.ncbi.nlm.nih.gov/pubmed/27626163
http://dx.doi.org/10.18632/oncotarget.11920