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Association mining of mutated cancer genes in different clinical stages across 11 cancer types

Many studies have demonstrated that some genes (e.g. APC, BRAF, KRAS, PTEN, TP53) are frequently mutated in cancer, however, underlying mechanism that contributes to their high mutation frequency remains unclear. Here we used Apriori algorithm to find the frequent mutational gene sets (FMGSs) from 4...

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Detalles Bibliográficos
Autores principales: Hu, Wangxiong, Li, Xiaofen, Wang, Tingzhang, Zheng, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356553/
https://www.ncbi.nlm.nih.gov/pubmed/27556693
http://dx.doi.org/10.18632/oncotarget.11392