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Activation of NLRP1 and NLRP3 inflammasomes contributed to cyclic stretch-induced pyroptosis and release of IL-1β in human periodontal ligament cells

Inflammasomes have been reported to be present in periodontal inflammatory tissue, but the exact role of inflammasomes in periodontal inflammatory reactions especially those related to mechanical stimulations has not been clarified. In this study, it was shown that cyclic stretch activated the nucle...

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Detalles Bibliográficos
Autores principales: Zhao, Dan, Wu, Yaqin, Zhuang, Jiabao, Xu, Chun, Zhang, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356555/
https://www.ncbi.nlm.nih.gov/pubmed/27626170
http://dx.doi.org/10.18632/oncotarget.11944