Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway

Both preclinical and epidemiology studies associate β-adrenoceptors-blockers (β-blockers) with activity against melanoma. However, the underlying mechanism is still unclear, especially in acral melanoma. In this study, we explored the effect of propranolol, a non-selective β-blocker, on the A375 mel...

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Detalles Bibliográficos
Autores principales: Zhou, Chengfang, Chen, Xiang, Zeng, Weiqi, Peng, Cong, Huang, Gang, Li, Xian'an, Ouyang, Zhengxiao, Luo, Yi, Xu, Xuezheng, Xu, Biaobo, Wang, Weili, He, Ruohui, Zhang, Xu, Zhang, Liyang, Liu, Jie, Knepper, Todd C., He, Yijing, McLeod, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356557/
https://www.ncbi.nlm.nih.gov/pubmed/27582542
http://dx.doi.org/10.18632/oncotarget.11599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356557/
https://www.ncbi.nlm.nih.gov/pubmed/27582542
http://dx.doi.org/10.18632/oncotarget.11599

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