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Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis

Clinically applicable platforms revealing actionable genomic alterations may improve the treatment efficacy of myeloma patients. In this pilot study, we used a high depth targeted sequencing panel containing 83 anti-cancer drug target genes to sequence genomic DNAs extracted from bone marrow aspirat...

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Detalles Bibliográficos
Autores principales: Kim, Seok Jin, Shin, Hyun-Tae, Lee, Hae-Ock, Kim, Nayoung K.D., Yun, Jae Won, Hwang, Jee Hyang, Kim, Kihyun, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356560/
https://www.ncbi.nlm.nih.gov/pubmed/27634910
http://dx.doi.org/10.18632/oncotarget.12029