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Two-stage induced differentiation of OCT4(+)/Nanog(+) stem-like cells in lung adenocarcinoma

Stem-like cells in solid tumors are purported to contribute to cancer development and poor treatment outcome. The abilities to self-renew, differentiate, and resist anticancer therapies are hallmarks of these rare cells, and steering them into lineage commitment may be one strategy to curb cancer de...

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Detalles Bibliográficos
Autores principales: Li, Rong, Huang, Jinsu, Ma, Meili, Lou, Yuqing, Zhang, Yanwei, Wu, Lixia, Chang, David W., Zhao, Picheng, Dong, Qianggang, Wu, Xifeng, Han, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356561/
https://www.ncbi.nlm.nih.gov/pubmed/27588392
http://dx.doi.org/10.18632/oncotarget.11721