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Antigen-specific T cell Redirectors: a nanoparticle based approach for redirecting T cells

Redirection of T cells to target and destroy tumors has become an important clinical tool and major area of research in tumor immunology. Here we present a novel, nanoparticle-based approach to selectively bind antigen-specific cytotoxic T cells (CTL) and redirect them to kill tumors, termed ATR (An...

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Detalles Bibliográficos
Autores principales: Schütz, Christian, Varela, Juan Carlos, Perica, Karlo, Haupt, Carl, Oelke, Mathias, Schneck, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356569/
https://www.ncbi.nlm.nih.gov/pubmed/27602488
http://dx.doi.org/10.18632/oncotarget.11785