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Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc(Min/+) model
Hepatocyte growth factor activator inhibitor type 1 (HAI-1), encoded by the Spint1 gene, is a membrane-bound serine protease inhibitor expressed on the epithelial cell surface. We have previously reported that the intestine-specific Spint1-deleted Apc(Min/+) mice showed accelerated formation of inte...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356577/ https://www.ncbi.nlm.nih.gov/pubmed/27612426 http://dx.doi.org/10.18632/oncotarget.11863 |