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Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction

Prostate cancer is the most common type of cancer diagnosed and the second leading cause of cancer-related death in American men. Natural Killer (NK) cells are the first line of defense against cancer and infections. NK cell function is regulated by a delicate balance between signals received throug...

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Detalles Bibliográficos
Autores principales: Mathew, Stephen O., Chaudhary, Pankaj, Powers, Sheila B., Vishwanatha, Jamboor K., Mathew, Porunelloor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356580/
https://www.ncbi.nlm.nih.gov/pubmed/27626681
http://dx.doi.org/10.18632/oncotarget.11896