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BIM deletion polymorphisms in Hispanic patients with non-small cell lung cancer carriers of EGFR mutations

BACKGROUND: Germline alterations in the proapoptotic protein Bcl-2-like 11 (BIM) can have a crucial role in diverse tumors. To determine the clinical utility of detecting BIM deletion polymorphisms (par4226 bp/ par363 bp) in EGFR positive non-small-cell lung cancer (NSCLC) we examined the outcomes o...

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Detalles Bibliográficos
Autores principales: Cardona, Andrés F., Rojas, Leonardo, Wills, Beatriz, Arrieta, Oscar, Carranza, Hernán, Vargas, Carlos, Otero, Jorge, Corrales-Rodriguez, Luis, Martín, Claudio, Reguart, Noemí, Archila, Pilar, Rodríguez, July, Cuello, Mauricio, Ortíz, Carlos, Franco, Sandra, Rolfo, Christian, Rosell, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356601/
https://www.ncbi.nlm.nih.gov/pubmed/27926478
http://dx.doi.org/10.18632/oncotarget.12112