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Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline

Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia. The mechanisms by which areca nut participates in OSCC tumorigenesis are not well understood. In this study, we investigated the effects of low dose l...

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Detalles Bibliográficos
Autores principales: Wang, Tung Yuan, Peng, Chih-Yu, Lee, Shiuan-Shinn, Chou, Ming-Yung, Yu, Cheng-Chia, Chang, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356645/
https://www.ncbi.nlm.nih.gov/pubmed/27557511
http://dx.doi.org/10.18632/oncotarget.11432