Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

Human endogenous retrovirus type K (HERV-K) Env protein was previously demonstrated to be overexpressed in human breast cancer (BC) cells and tissues. However, the molecular pathways driving the specific alterations are unknown. We now show that knockdown of its expression with an shRNA (shRNAenv) b...

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Detalles Bibliográficos
Autores principales: Zhou, Fuling, Li, Ming, Wei, Yongchang, Lin, Kevin, Lu, Yue, Shen, Jianjun, Johanning, Gary L., Wang-Johanning, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356647/
https://www.ncbi.nlm.nih.gov/pubmed/27557521
http://dx.doi.org/10.18632/oncotarget.11455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356647/
https://www.ncbi.nlm.nih.gov/pubmed/27557521
http://dx.doi.org/10.18632/oncotarget.11455

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