Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

Recent evidence suggests that inhibition of protein phosphatase 2A (PP2A) tumor suppressor activity via the SET oncoprotein contributes to the pathogenesis of various cancers. Here we demonstrate that both SET and c-MYC expression are frequently elevated in T-ALL cell lines and primary samples compa...

Descripción completa

Detalles Bibliográficos
Autores principales: Richard, Nameeta P., Pippa, Raffaella, Cleary, Megan M., Puri, Alka, Tibbitts, Deanne, Mahmood, Shawn, Christensen, Dale J., Jeng, Sophia, McWeeney, Shannon, Look, A. Thomas, Chang, Bill H., Tyner, Jeffrey W., Vitek, Michael P., Odero, María D., Sears, Rosalie, Agarwal, Anupriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356656/
https://www.ncbi.nlm.nih.gov/pubmed/27705940
http://dx.doi.org/10.18632/oncotarget.12394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356656/
https://www.ncbi.nlm.nih.gov/pubmed/27705940
http://dx.doi.org/10.18632/oncotarget.12394

Ejemplares similares