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Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma

Dicer, a key component of the microRNA processing machinery, has been reported to exert discrepant prognostic values and biological roles in different types of cancers. Here, we investigated the function and prognostic value of Dicer in clear cell renal cell carcinoma (ccRCC). Using the retrospectiv...

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Detalles Bibliográficos
Autores principales: Chen, Yan-Su, Meng, Fei, Li, Hai-Long, Liu, Qing-Hua, Hou, Ping-Fu, Bai, Jin, Zheng, Jun-Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356663/
https://www.ncbi.nlm.nih.gov/pubmed/27732931
http://dx.doi.org/10.18632/oncotarget.12520