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FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

FOXC1 is a member of Forkhead box family transcription factors. We showed that FOXC1 level was increased in melanoma cells and tissues and correlated with hypomethylation of the FOXC1 gene. Overexpression of FOXC1 promoted proliferation, migration, invasion, colony formation and growth in 3D Matrige...

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Detalles Bibliográficos
Autores principales: Wang, Jinhua, Li, Li, Liu, Shiwei, Zhao, Ying, Wang, Lin, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356666/
https://www.ncbi.nlm.nih.gov/pubmed/27533251
http://dx.doi.org/10.18632/oncotarget.11224