Cargando…
FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma
FOXC1 is a member of Forkhead box family transcription factors. We showed that FOXC1 level was increased in melanoma cells and tissues and correlated with hypomethylation of the FOXC1 gene. Overexpression of FOXC1 promoted proliferation, migration, invasion, colony formation and growth in 3D Matrige...
Autores principales: | Wang, Jinhua, Li, Li, Liu, Shiwei, Zhao, Ying, Wang, Lin, Du, Guanhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356666/ https://www.ncbi.nlm.nih.gov/pubmed/27533251 http://dx.doi.org/10.18632/oncotarget.11224 |
Ejemplares similares
-
FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer
por: Wang, Jinhua, et al.
Publicado: (2016) -
FOXCUT Promotes the Proliferation and Invasion by Activating FOXC1/PI3K/AKT Pathway in Colorectal Cancer
por: Zhang, Xiaojie, et al.
Publicado: (2020) -
Phosphorylated Akt1 expression is associated with poor prognosis in cutaneous, oral and sinonasal melanomas
por: Soares, Ciro, et al.
Publicado: (2018) -
MiR-5195-3p targets the PCBP2/PI3K/AKT pathway to inhibit melanoma cell proliferation and migration
por: Yang, Botao, et al.
Publicado: (2023) -
The multi-faceted roles of the PI3K-AKT pathway in melanoma
por: Davies, Michael A
Publicado: (2015)