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Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors
γδ T cells has been shown to exhibit profound antitumor effects in a broad range of tumor entities, including OS. However, resistance to γδ T cells is a serious problem in the management of OS. This study investigates the impact of celastrol on the expression of death receptors 4/5 (DR4/5) on OS cel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356667/ https://www.ncbi.nlm.nih.gov/pubmed/27768597 http://dx.doi.org/10.18632/oncotarget.12756 |