PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

Nuclear receptors such as peroxisome proliferator-activated receptor α (PPARα) are potential therapeutic targets. In this study, we found that PPARα expression was lower in high grade gliomas and PPARα was an independent prognostic factor in GBM patients. PPARα agonism or overexpression inhibited gl...

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Detalles Bibliográficos
Autores principales: Shi, Yan, Tao, Tao, Liu, Ning, Luan, WenKang, Qian, Jin, Li, Rui, Hu, Qi, Wei, Yan, Zhang, Junxia, You, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356686/
https://www.ncbi.nlm.nih.gov/pubmed/27835866
http://dx.doi.org/10.18632/oncotarget.13170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356686/
https://www.ncbi.nlm.nih.gov/pubmed/27835866
http://dx.doi.org/10.18632/oncotarget.13170

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