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PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop
Nuclear receptors such as peroxisome proliferator-activated receptor α (PPARα) are potential therapeutic targets. In this study, we found that PPARα expression was lower in high grade gliomas and PPARα was an independent prognostic factor in GBM patients. PPARα agonism or overexpression inhibited gl...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356686/ https://www.ncbi.nlm.nih.gov/pubmed/27835866 http://dx.doi.org/10.18632/oncotarget.13170 |