Cargando…

Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells

Lethal progression of prostate cancer metastasis can be improved by developing animal models that recapitulate the clinical conditions. We report here that cytokeratin 13 (KRT13), an intermediate filament protein, plays a directive role in prostate cancer bone, brain, and soft tissue metastases. KRT...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qinlong, Yin, Lijuan, Jones, Lawrence W., Chu, Gina C-Y, Wu, Jason B-Y., Huang, Jen-Ming, Li, Quanlin, You, Sungyong, Kim, Jayoung, Lu, Yi-Tsung, Mrdenovic, Stefan, Wang, Ruoxiang, Freeman, Michael R., Garraway, Isla, Lewis, Michael S., Chung, Leland W. K., Zhau, Haiyen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356688/
https://www.ncbi.nlm.nih.gov/pubmed/27835867
http://dx.doi.org/10.18632/oncotarget.13175