The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation

Mitotic progression is crucial for the maintenance of chromosomal stability. A proper progression is ensured by the activities of multiple kinases. One of these enzymes, the serine/threonine kinase Aurora A, is required for proper mitosis through the regulation of centrosome and spindle assembly. In...

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Detalles Bibliográficos
Autores principales: Min, Yoo Hong, Kim, Wootae, Kim, Ja-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356694/
https://www.ncbi.nlm.nih.gov/pubmed/27713168
http://dx.doi.org/10.18632/oncotarget.12448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356694/
https://www.ncbi.nlm.nih.gov/pubmed/27713168
http://dx.doi.org/10.18632/oncotarget.12448

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