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Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction
BCR/Abl protein drives the onset and progression of Chronic Myeloid Leukemia (CML). We previously showed that BCR/Abl protein is suppressed in low oxygen, where viable cells retain stem cell potential. This study addressed the regulation of BCR/Abl protein expression under oxygen or glucose shortage...
Autores principales: | Bono, Silvia, Lulli, Matteo, D'Agostino, Vito Giuseppe, Gesualdo, Federico Di, Loffredo, Rosa, Cipolleschi, Maria Grazia, Provenzani, Alessandro, Rovida, Elisabetta, Sbarba, Persio Dello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356700/ https://www.ncbi.nlm.nih.gov/pubmed/27852045 http://dx.doi.org/10.18632/oncotarget.13319 |
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