Hepatitis B virus X protein influences enrichment profiles of H3K9me3 on promoter regions in human hepatoma cell lines

We previously showed that hepatitis B virus (HBV) X protein (HBx) could promote the trimethylation of histone H3 lysine 9 (H3K9me3) to repress tumor suppressor genes in hepatocellular carcinoma (HCC). In this work, we analyze 23,148 human promoters using ChIP-chip to determine the effects of HBx on...

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Detalles Bibliográficos
Autores principales: Wang, Di-Yi, An, Shu-Hong, Liu, Lei, Bai, Shan-Shan, Wu, Kai-Xiang, Zhu, Rong, Wang, Zhao-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356706/
https://www.ncbi.nlm.nih.gov/pubmed/27768594
http://dx.doi.org/10.18632/oncotarget.12751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356706/
https://www.ncbi.nlm.nih.gov/pubmed/27768594
http://dx.doi.org/10.18632/oncotarget.12751

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