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MKP-1 attenuates LPS-induced blood-testis barrier dysfunction and inflammatory response through p38 and IκBα pathways

Sertoli cells create a local tolerogenic microenvironment to maintain testicular immune privilege especially through the formation of a blood-testis barrier (BTB). However, the molecular mechanisms underlying the immune modulation function and BTB dynamics of Sertoli cells remained elusive. MAP phos...

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Detalles Bibliográficos
Autores principales: Pan, Yiqing, Liu, Yue, Wang, Li, Xue, Feng, Hu, Yanqin, Hu, Ran, Xu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356708/
https://www.ncbi.nlm.nih.gov/pubmed/27783995
http://dx.doi.org/10.18632/oncotarget.12823