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EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells

Epithelial-mesenchymal transition (EMT) can contribute to tumor invasion, metastasis, and resistance to chemotherapy or hormone therapy. EMT may be induced by a variety of growth factors, such as epidermal growth factor (EGF). Most studies regarding EMT have focused on TGF-β-Smads signaling. The mec...

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Detalles Bibliográficos
Autores principales: Kim, Jinkyoung, Kong, Jienan, Chang, Hyeyoon, Kim, Hayeon, Kim, Aeree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356716/
https://www.ncbi.nlm.nih.gov/pubmed/27829223
http://dx.doi.org/10.18632/oncotarget.13116