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Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer

COX-2 expression level and prognostic value are still a matter of debate in breast cancer (BC). We addressed these points in the context of PIK3CA mutational status. Based on an interesting study of aspirin efficacy in colorectal cancer, we hypothesized that celecoxib antitumoral activity may be res...

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Detalles Bibliográficos
Autores principales: Tury, Sandrine, Becette, Véronique, Assayag, Franck, Vacher, Sophie, Benoist, Camille, Kamal, Maud, Marangoni, Elisabetta, Bièche, Ivan, Lerebours, Florence, Callens, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356723/
https://www.ncbi.nlm.nih.gov/pubmed/27835884
http://dx.doi.org/10.18632/oncotarget.13200