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CXCR4 antagonists suppress small cell lung cancer progression

Small cell lung cancer (SCLC) is an aggressive tumor with poor prognosis due to early metastatic spread and development of chemoresistance. Playing a key role in tumor-stroma interactions the CXCL12-CXCR4 axis may be involved in both processes and thus represent a promising therapeutic target in SCL...

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Detalles Bibliográficos
Autores principales: Taromi, Sanaz, Kayser, Gian, Catusse, Julie, von Elverfeldt, Dominik, Reichardt, Wilfried, Braun, Friederike, Weber, Wolfgang A., Zeiser, Robert, Burger, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356728/
https://www.ncbi.nlm.nih.gov/pubmed/27835905
http://dx.doi.org/10.18632/oncotarget.13238