YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process

We previously observed reduced YWHAE (14-3-3ε) protein expression in a small set of gastric cancer samples. YWHAE may act as a negative regulator of the cyclin CDC25B, which is a transcriptional target of MYC oncogene. The understanding of YWHAE role and its targets is important for the better knowl...

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Detalles Bibliográficos
Autores principales: Leal, Mariana Ferreira, Ribeiro, Helem Ferreira, Rey, Juan Antonio, Pinto, Giovanny Rebouças, Smith, Marília Cardoso, Moreira-Nunes, Caroline Aquino, Assumpção, Paulo Pimentel, Lamarão, Leticia Martins, Calcagno, Danielle Queiroz, Montenegro, Raquel Carvalho, Burbano, Rommel Rodriguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356744/
https://www.ncbi.nlm.nih.gov/pubmed/27863420
http://dx.doi.org/10.18632/oncotarget.13381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356744/
https://www.ncbi.nlm.nih.gov/pubmed/27863420
http://dx.doi.org/10.18632/oncotarget.13381

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