Synergistic antitumor activity of the combination of salubrinal and rapamycin against human cholangiocarcinoma cells

Less is known about the roles of eukaryotic initiation factor alpha (eIF2α) in cholangiocarcinoma (CCA). Here, we report that eIF2α inhibitor salubrinal inhibits the proliferation of human CCA cells. Clinical application of mammalian target of rapamycin (mTOR) inhibitors only has moderate antitumor...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaofang, Zhang, Chunyan, Zhou, Hong, Xiao, Bin, Cheng, Ying, Wang, Jinju, Yao, Fuli, Duan, Chunyan, Chen, Run, Liu, Youping, Feng, Chunhong, Li, Hong, Li, Jing, Dai, Rongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356752/
https://www.ncbi.nlm.nih.gov/pubmed/27863431
http://dx.doi.org/10.18632/oncotarget.13408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356752/
https://www.ncbi.nlm.nih.gov/pubmed/27863431
http://dx.doi.org/10.18632/oncotarget.13408

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