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Negative regulation of REST on NR2B in spinal cord contributes to the development of bone cancer pain in mice
In this study, C3H/HeNCrlVr mice are implanted with sarcoma NCTC 2472 cells into the intramedullary space of the femur to induce ongoing bone cancer-related pain behaviors. During the progress of the bone cancer pain, the down-regulation in spinal REST (Neuron-restrictive silencer factor, NRSF/REST)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356758/ https://www.ncbi.nlm.nih.gov/pubmed/27732941 http://dx.doi.org/10.18632/oncotarget.9447 |