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Negative regulation of REST on NR2B in spinal cord contributes to the development of bone cancer pain in mice

In this study, C3H/HeNCrlVr mice are implanted with sarcoma NCTC 2472 cells into the intramedullary space of the femur to induce ongoing bone cancer-related pain behaviors. During the progress of the bone cancer pain, the down-regulation in spinal REST (Neuron-restrictive silencer factor, NRSF/REST)...

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Detalles Bibliográficos
Autores principales:	Wang, Dan, Yu, Jianbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356758/ https://www.ncbi.nlm.nih.gov/pubmed/27732941 http://dx.doi.org/10.18632/oncotarget.9447

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