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Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2

Polycomb group proteins regulate chromatin structure and have an important regulatory role on gene expression in various cell types. Two polycomb group complexes (Polycomb repressive complex 1 (PRC1) and 2 (PRC2)) have been identified in mammalian cells. Both PRC1 and PRC2 compact chromatin, and als...

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Detalles Bibliográficos
Autores principales: Christofides, Anthos, Karantanos, Theodoros, Bardhan, Kankana, Boussiotis, Vassiliki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356764/
https://www.ncbi.nlm.nih.gov/pubmed/27793053
http://dx.doi.org/10.18632/oncotarget.12928