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The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors

Central nervous system tumors are the most common cancer type in children and the leading cause of cancer related deaths. There is therefore a need to develop novel treatments. Large scale profiling studies have begun to identify alterations that could be targeted therapeutically, including the phos...

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Detalles Bibliográficos
Autores principales: Rogers, Hazel A., Estranero, Jasper, Gudka, Keshni, Grundy, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356782/
https://www.ncbi.nlm.nih.gov/pubmed/27926496
http://dx.doi.org/10.18632/oncotarget.13781