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Droplet digital PCR is a powerful technique to demonstrate frequent FGFR1 duplication in dysembryoplastic neuroepithelial tumors

Dysembryoplastic neuroepithelial tumors (DNT) share V600E mutation in the BRAF gene with other low grade neuroepithelial tumors (LGNTs). FGFR1 internal tandem duplication of the tyrosine-kinase domain (FGFR1-ITD), another genetic alteration that also leads to MAP kinase pathway alteration, has been...

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Detalles Bibliográficos
Autores principales: Fina, Frédéric, Barets, Doriane, Colin, Carole, Bouvier, Corinne, Padovani, Laëtitia, Nanni-Metellus, Isabelle, Ouafik, L’Houcine, Scavarda, Didier, Korshunov, Andrey, Jones, David T.W., Figarella-Branger, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356784/
https://www.ncbi.nlm.nih.gov/pubmed/27791984
http://dx.doi.org/10.18632/oncotarget.12881