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Definition and characterization of novel HLA-*A02-restricted CD8(+) T cell epitopes derived from JCV polyomavirus with clinical relevance

Human JC and BK polyomaviruses (JCV/BKV) can establish a latent infection without any clinical symptoms in healthy individuals. In immunocompromised hosts infection or reactivation of JCV and BKV can cause lethal progressive multifocal leukoencephalopathy (PML) and hemorrhagic cystitis, respectively...

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Detalles Bibliográficos
Autores principales: Mani, Jiju, Wang, Lei, Hückelhoven, Angela G., Schmitt, Anita, Gedvilaite, Alma, Jin, Nan, Kleist, Christian, Ho, Anthony D, Schmitt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356818/
https://www.ncbi.nlm.nih.gov/pubmed/27705933
http://dx.doi.org/10.18632/oncotarget.12387