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Definition and characterization of novel HLA-*A02-restricted CD8(+) T cell epitopes derived from JCV polyomavirus with clinical relevance
Human JC and BK polyomaviruses (JCV/BKV) can establish a latent infection without any clinical symptoms in healthy individuals. In immunocompromised hosts infection or reactivation of JCV and BKV can cause lethal progressive multifocal leukoencephalopathy (PML) and hemorrhagic cystitis, respectively...
Autores principales: | Mani, Jiju, Wang, Lei, Hückelhoven, Angela G., Schmitt, Anita, Gedvilaite, Alma, Jin, Nan, Kleist, Christian, Ho, Anthony D, Schmitt, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356818/ https://www.ncbi.nlm.nih.gov/pubmed/27705933 http://dx.doi.org/10.18632/oncotarget.12387 |
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