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Y-box binding protein-1 promotes hepatocellular carcinoma-initiating cell progression and tumorigenesis via Wnt/β-catenin pathway

Y-box binding protein-1 (YB-1) is a pleiotropic molecule that binds DNA to regulate genes on a transcriptional level in the nucleus and binds RNA to modulate gene translation in the cytoplasm. In our previous studies, YB-1 was also characterized as a fetal hepatic protein that regulates the maturati...

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Detalles Bibliográficos
Autores principales: Chao, Hsiao-Mei, Huang, Hong-Xuan, Chang, Po-Hsiang, Tseng, Kuo-Chang, Miyajima, Atsushi, Chern, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356827/
https://www.ncbi.nlm.nih.gov/pubmed/27911878
http://dx.doi.org/10.18632/oncotarget.13733