IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM)

Cancer immunotherapy has been shown to enhance established treatment regimens. We evaluated the potential reinforcing effect of IL-15 in trastuzumab treated humanized tumor mice (HTM) which were generated by concurrent transplantation of neonatal NOD-scid IL2Rγnull mice with human hematopoietic stem...

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Detalles Bibliográficos
Autores principales: Wege, Anja K, Weber, Florian, Kroemer, Alexander, Ortmann, Olaf, Nimmerjahn, Falk, Brockhoff, Gero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356837/
https://www.ncbi.nlm.nih.gov/pubmed/27835865
http://dx.doi.org/10.18632/oncotarget.13159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356837/
https://www.ncbi.nlm.nih.gov/pubmed/27835865
http://dx.doi.org/10.18632/oncotarget.13159

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